Association between non-alcoholic fatty liver disease and risk of incident heart failure: a meta-analysis of observational studies.

ABSTRACT:

Background and aims

Recent research has associated non-alcoholic fatty liver disease (NAFLD) with an increased risk of atherosclerotic cardiovascular disease. Previous studies that evaluated the association between NAFLD and risk of heart failure (HF) yielded inconsistent results, however. This meta-analysis aimed to evaluate the association between NAFLD and the risk of HF.

Methods

We searched multiple electronic databases, including PubMed, Google Scholar, Embase and Web of Science for potential studies published from inception until 30 October 2021. Cohort studies reported multivariable-adjusted risks of incident HF in NAFLD patients comparing those without NAFLD were included.

Results

Six cohort studies comprising 10,979,967 participants (women = 55.5%) were inclu

SUBMITTER: Li W 

PROVIDER: S-EPMC9425885 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature