Tailoring Multi-omics to Inflammatory Bowel Diseases: All for One and One for All.

ABSTRACT: Inflammatory bowel disease [IBD] has a multifactorial origin and originates from a complex interplay of environmental factors with the innate immune system at the intestinal epithelial interface in a genetically susceptible individual. All these factors make its aetiology intricate and largely unknown. Multi-omic datasets obtained from IBD patients are required to gain further insights into IBD biology. We here review the landscape of multi-omic data availability in IBD and identify barriers and gaps for future research. We also outline the various technical and non-technical factors that influence the utility and interpretability of multi-omic datasets and thereby the study design of any research project generating such datasets. Coordinated generation of multi-omic datasets and their sys

SUBMITTER: Sudhakar P 

PROVIDER: S-EPMC9426669 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature