Integrating genomic and epidemiologic data to accelerate progress toward schistosomiasis elimination.

ABSTRACT: The global community has adopted ambitious goals to eliminate schistosomiasis as a public health problem, and new tools are needed to achieve them. Mass drug administration programs, for example, have reduced the burden of schistosomiasis, but the identification of hotspots of persistent and reemergent transmission threaten progress toward elimination and underscore the need to couple treatment with interventions that reduce transmission. Recent advances in DNA sequencing technologies make whole-genome sequencing a valuable and increasingly feasible option for population-based studies of complex parasites such as schistosomes. Here, we focus on leveraging genomic data to tailor interventions to distinct social and ecological circumstances. We consider two priority questions that can be add

SUBMITTER: Lund AJ 

PROVIDER: S-EPMC9427098 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature