Reliability and acceptance of dreaMS, a software application for people with multiple sclerosis: a feasibility study.

ABSTRACT:

Background

There is an unmet need for reliable and sensitive measures for better monitoring people with multiple sclerosis (PwMS) to detect disease progression early and adapt therapeutic measures accordingly.

Objective

To assess reliability of extracted features and meaningfulness of 11 tests applied through a smartphone application ("dreaMS").

Methods

PwMS (age 18-70 and EDSS ≤ 6.5) and matched healthy volunteers (HV) were asked to perform tests installed on their smartphone once or twice weekly for 5 weeks. Primary outcomes were test-retest reliability of test features (target: intraclass correlation [ICC] ≥ 0.6 or median coefficient of variation [mCV] < 0.2) and reported meaningfulness of the tests by PwMS. Meaningfulness was self-assessed for each test on a 5-poi

SUBMITTER: Woelfle T 

PROVIDER: S-EPMC9427170 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature