HBV epidemiology and genetic diversity in an area of high prevalence of hepatitis B in southern Brazil.

ABSTRACT:

Background

Hepatitis B virus (HBV) infection is a major public health problem in Brazil. HBV endemicity is usually moderate to low according to geographic regions, and high prevalence of this virus has been reported in people of some specific Brazilian counties, including those with a strong influence of Italian colonization in southern Brazil. Analysis of HBV diversity and identification of the main risk factors to HBV infection are necessary to understand hepatitis B epidemiology in these high prevalence regions in southern Brazil.

Objective

To investigate epidemiological characteristics and HBV genotypes and subgenotypes circulating in a specific city with high HBV prevalence.

Methods

A cross-sectional study was performed with 102 HBV chronically infected individua

SUBMITTER: Paoli J 

PROVIDER: S-EPMC9427806 | biostudies-literature | 2018 Jul - Aug

REPOSITORIES: biostudies-literature