Screening, molecular simulation & in silico kinetics of virtually designed covid-19 main protease inhibitors.

ABSTRACT: Coronavirus (covid-19) infection is considered to be deadliest ever pandemic experienced by the human being. It has very badly affected the socio-economic health of human and stuck the scientific community to think and rethink about its complete eradication. But due to no effective treatment or unavailability of vaccine the health professional could not show any significant improvement to control the pandemic. The situation needs newer molecule, vaccine or effective treatment to control covid-19 infection. Different target in viruses has been explored and proteases enzymes were found to be therapeutically effective target for the design of potential anti-covid-19 molecule as it plays the vital role in viral replication and assembly. Structure-based drug design was employed to discover the

SUBMITTER: Aleissa MS 

PROVIDER: S-EPMC9428119 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature