Dataset Information

Computing semantic similarity of texts based on deep graph learning with ability to use semantic role label information.

ABSTRACT: We propose a deep graph learning approach for computing semantic textual similarity (STS) by using semantic role labels generated by a Semantic Role Labeling (SRL) system. SRL system output has significant challenges in dealing with graph-neural networks because it doesn't have a graph structure. To address these challenges, we propose a novel SRL graph by using semantic role labels and dependency grammar. For processing the SRL graph, we proposed a Deep Graph Neural Network (DGNN) based graph-U-Net model that is placed on top of the transformers to use a variety of transformers to process representations obtained from them. We investigate the effect of using the proposed DGNN and SRL graph on the performance of some transformers in computing STS. For the evaluation of our approach, we use STS2017 and SICK datasets. Experimental evaluations show that using the SRL graph accompanied by applying the proposed DGNN increases the performance of the transformers used in the DGNN.

SUBMITTER: Mohebbi M

PROVIDER: S-EPMC9428166 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Computing semantic similarity of texts based on deep graph learning with ability to use semantic role label information.

Mohebbi Majid M Razavi Seyed Naser SN Balafar Mohammad Ali MA

Scientific reports 20220830 1

We propose a deep graph learning approach for computing semantic textual similarity (STS) by using semantic role labels generated by a Semantic Role Labeling (SRL) system. SRL system output has significant challenges in dealing with graph-neural networks because it doesn't have a graph structure. To address these challenges, we propose a novel SRL graph by using semantic role labels and dependency grammar. For processing the SRL graph, we proposed a Deep Graph Neural Network (DGNN) based graph-U ...[more]

PMID: 36042274

Similar Datasets

Project description:Cellular senescence is a primordial driver of tissue and organ aging, and the accumulation of senescent cells (SnCs) has been implicated in numerous age-related diseases. A major barrier to studying senescence is the rarity and heterogeneity of SnCs, which are not a uniform population but instead comprise diverse senotypes shaped by cell-of-origin and microenvironmental context. Such heterogeneity exceeds what classical senescence hallmarks can resolve at single-cell resolution, motivating the need for computational frameworks that can capture senotype-level diversity intrinsically. Here, we introduce DeepSAS, a deep graph representation learning framework that robustly identifies cell-type-specific SnCs and their senescence-associated genes (SnGs). DeepSAS incorporates a heterogeneous graph that integrates intracellular transcriptional states with intercellular communication cues, enabling the joint inference of senescent cells and senescence-linked genes through attention-based contrastive learning. Applied to public healthy eye and lung atlases, DeepSAS identified SnCs whose proportions positively correlate with aging. From in-house idiopathic pulmonary fibrosis (IPF) patient scRNA-seq data, DeepSAS detected 1,678 SnCs (out of 24,125 cells) and 263 SnGs across 26 cell types, including 43 SnGs that are uniquely associated with a single cell type. We generated high-resolution Xenium spatial transcriptomics data to further validate SnGs in IPF, revealing NFE2L2 as a SnG specifically enriched in CTHRC1+ fibroblasts. Notably, the ex vivo bleomycin-induced senescence in human precision-cut lung slice (hPCLS) samples similarly identified NFE2L2 as an SnG in CTHRC1+ fibroblasts, albeit with stronger transcriptional signals, suggesting mechanistic differences in senescence cells associated with chronic and acute injury. Overall, DeepSAS uncovers distinct senescence programs and infers cell-type-specific SnGs that are difficult to resolve using existing marker-based approaches. We believe it offers a generalizable and translationally relevant strategy for advancing senescence biology and therapeutic development.

Dataset Information

Computing semantic similarity of texts based on deep graph learning with ability to use semantic role label information.

Publications

Computing semantic similarity of texts based on deep graph learning with ability to use semantic role label information.

Similar Datasets

OmicsDI is part of the ELIXIR infrastructure

Tweets