Human herpesvirus 6A active infection in patients with autoimmune Hashimoto's thyroiditis.

ABSTRACT:

Background

Hypothyroidism due to Hashimoto's thyroiditis (HT) is the commonest autoimmune endocrine illness in which antibodies against thyroid organ result in inflammation. The disease has a complex etiology that involves genetic and environmental influences. Viral infections may be involved in triggering of the disease as their molecular mimicry enhance autoimmune responses. Human herpesvirus-6 (HHV-6) is recognized for its contribution to some autoimmune diseases.

Objective

In the current study, the prevalence of HHV-6 active infection in patients with HT and with non-autoimmune thyroid disorders were compared with patients with euthyroidism. In addition, a correlation between presence of HHV-6 infections and HT was investigated.

Methods

A total of 151 patients wit

SUBMITTER: Seyyedi N 

PROVIDER: S-EPMC9428182 | biostudies-literature | 2019 Nov - Dec

REPOSITORIES: biostudies-literature