Dynamic risk prediction of BK polyomavirus reactivation after renal transplantation.

ABSTRACT:

Purpose

To construct a dynamic prediction model for BK polyomavirus (BKV) reactivation during the early period after renal transplantation and to provide a statistical basis for the identification of and intervention for high-risk populations.

Methods

A retrospective study of 312 first renal allograft recipients with strictly punctual follow-ups was conducted between January 2015 and March 2022. The covariates were screened using univariable time-dependent Cox regression, and those with P<0.1 were included in the dynamic and static analyses. We constructed a prediction model for BKV reactivation from 2.5 to 8.5 months after renal transplantation using dynamic Cox regression based on the landmarking method and evaluated its performance using the area under the curve (AUC) val

SUBMITTER: Fang Y 

PROVIDER: S-EPMC9428263 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature