Evaluating the clinical relevance of the enterotypes in the Estonian microbiome cohort.

ABSTRACT: Human gut microbiome is subject to high inter-individual and temporal variability, which complicates building microbiome-based applications, including applications that can be used to improve public health. Categorizing the microbiome profiles into a small number of distinct clusters, such as enterotyping, has been proposed as a solution that can ameliorate these shortcomings. However, the clinical relevance of the enterotypes is poorly characterized despite a few studies marking the potential for using the enterotypes for disease diagnostics and personalized nutrition. To gain a further understanding of the clinical relevance of the enterotypes, we used the Estonian microbiome cohort dataset (n = 2,506) supplemented with diagnoses and drug usage information from electronic health r

SUBMITTER: Aasmets O 

PROVIDER: S-EPMC9428584 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature