Comparison of different metrics of cerebral autoregulation in association with major morbidity and mortality after cardiac surgery.

ABSTRACT:

Background

Cardiac surgery studies have established the clinical relevance of personalised arterial blood pressure management based on cerebral autoregulation. However, variabilities exist in autoregulation evaluation. We compared the association of several cerebral autoregulation metrics, calculated using different methods, with outcomes after cardiac surgery.

Methods

Autoregulation was measured during cardiac surgery in 240 patients. Mean flow index and cerebral oximetry index were calculated as Pearson's correlations between mean arterial pressure (MAP) and transcranial Doppler blood flow velocity or near-infrared spectroscopy signals. The lower limit of autoregulation and optimal mean arterial pressure were identified using mean flow index and cerebral oximetry index. Re

SUBMITTER: Liu X 

PROVIDER: S-EPMC9428920 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature