Novel lower-extremity dexterity assessment for Parkinson's disease: validation against measures of arm dexterity and general mobility.

ABSTRACT:

Purpose

To establish criterion and construct validity of a novel, clinically feasible assessment of lower-extremity dexterity for PD patients.

Methods

Thirty-three PD patients performed a unilateral lower-extremity dexterity task "off" and "on" dopaminergic medications with each leg. The task involves iteratively tapping targets with the foot in a specified pattern, and the measured outcome is the time to complete the movement sequence, with longer times indicating worse performance. We correlated leg movement time with standard, validated measures of gait (comfortable and maximal walk speeds), general mobility (timed up and go), upper-extremity dexterity (9-Hole Pegboard), and elements of the Unified Parkinson Disease Rating Scale (MDS-UPDRS).

Results

We found signif

SUBMITTER: Kuhman D 

PROVIDER: S-EPMC9428931 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature