Prognostic factors and scoring systems associated with outcome in pediatric acute liver failure.

ABSTRACT:

Background

Pediatric acute liver failure (PALF) is an uncommon, devastating illness with significant mortality. Liver transplantation remains the mainstay of treatment for irreversible PALF. The purpose of this study was to determine the etiology and prognostic factors associated with outcome of PALF in South Africa and to evaluate prognostic scoring systems used.

Methods

Records of 45 pediatric patients younger than 16 years of age who presented with PALF from 1 January 2015 till 31 October 2020 were analysed. Patients were divided into two groups with one group consisting of patients with spontaneous recovery of the liver with supportive treatment (6/45:13.3%) and the second group consisting of patients with poor outcomes who demised (19/45: 42%) or underwent liver transpl

SUBMITTER: Walabh P 

PROVIDER: S-EPMC9429365 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature