Investigating the paradox of increasing obesity and declining heart disease mortality in the United States: Age-period-cohort model.

ABSTRACT:

Background

Obesity as a risk factor of heart disease (HD) is confirmed through observational, laboratory, and intervention studies. However, it cannot explain why HD declines, but obesity increases in the United States in recent decades. This study attempted to understand this paradox.

Methods

Annual data of national HD mortality (1999-2018) were derived from Wide-Ranging Online Data for Epidemiologic Research, biannual obesity data (1999-2016) from the National Health and Nutrition Examination Survey, and smoking data (1965-1990) were from the National Health Interview Survey. Age-period-cohort method was used to decompose HD mortality into age, period, and cohort effects, and to estimate age-cohort adjusted mortality rates. To explain the paradox, age-cohort adjusted rates

SUBMITTER: Yu B 

PROVIDER: S-EPMC9429831 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature