Molecular Characterization of bla_NDM-Carrying IncX3 Plasmids: bla_NDM-16b Likely Emerged from a Mutation of bla_NDM-5 on IncX3 Plasmid.

ABSTRACT: Dissemination of bla_NDM, which is carried on the IncX3 plasmid, among Enterobacterales has been reported worldwide. In particular, bla_NDM-5-carrying IncX3 plasmids can spread among several hosts, facilitating their dissemination. Other variants, such as bla_NDM-17-, bla_NDM-19-, bla_NDM-20-, bla_NDM-21-, and bla_NDM-33-carrying IncX3 plasmids, have also been reported. Here, we characterized, using whole-genome sequencing (WGS), a bla_NDM-16b-carrying IncX3 plasmid harbored by Escherichia coli strain TA8571, which was isolated from a urine specimen of a hospital inpatient in Tokyo, Japan. The bla_NDM-16b differed in sequence from <

SUBMITTER: Ariyoshi T 

PROVIDER: S-EPMC9430178 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature