Clonal and Horizontal Transmission of <i>bla</i>_NDM among Klebsiella pneumoniae in Children's Intensive Care Units.

ABSTRACT: Increasing infections caused by bla_NDM-carrying Klebsiella pneumoniae (NDM-KP) are an urgent threat to children with weakened immunity and limited antibiotic use. Preventing and intervening in NDM-KP infections requires a clear understanding of the pathogen's molecular and epidemiological characteristics. We investigated the prevalence and characteristics of NDM-KP in six children's hospitals from five Chinese provinces/municipalities. We collected 111 NDM-KP strains (40 NDM-1, one NDM-4 and 70 NDM-5) from neonatal intensive care units (NICUs) and pediatric intensive care units (PICUs) from June 2017 to June 2018; these strains accounted for 31.62% of all carbapenem-resistant K. pneumoniae (CR-KP). Although NDM-KP isolates exhibited high resistance to all carbapenems, inc

SUBMITTER: Fu B 

PROVIDER: S-EPMC9431529 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature