Serum Cystatin C as a predictor of acute kidney injury in neonates: a meta-analysis.

ABSTRACT:

Objectives

The objective of this meta-analysis is to evaluate the diagnostic value of serum Cystatin C in acute kidney injury (AKI) in neonates.

Sources

PubMed, Embase, Cochrane Library, Web of Science, China National Knowledge Infrastructure (CNKI), and WanFang Database were searched to retrieve the literature related to the diagnostic value of Cystatin C for neonatal AKI from inception to May 10, 2021. Subsequently, the quality of included studies was determined using the QUADAS-2 tool. Stata 15.0 statistical software was used to calculate the combined sensitivity (SEN), specificity (SPE), positive likelihood ratio (PLR), negative likelihood ratio (NLR), and diagnostic odds ratio (DOR). Additionally, meta-regression analysis and subgroup analysis contributed to explore the

SUBMITTER: Yang H 

PROVIDER: S-EPMC9432009 | biostudies-literature | 2022 May-Jun

REPOSITORIES: biostudies-literature