Cord blood bilirubin and prediction of neonatal hyperbilirubinemia and perinatal infection in newborns at risk of hemolysis.

ABSTRACT:

Objective

To assess the accuracy of umbilical cord bilirubin values to predict jaundice in the first 48h of life and neonatal infection.

Method

Newborn infants treated at a regional well-baby nursery born at ≥36 weeks of gestation were included in this retrospective cohort study. All infants born in a 3-year period from mothers with O blood type and/or Rh-negative were included and had the umbilical cord bilirubin levels measured. Hyperbilirubinemia in the first 48h was defined as bilirubin levels above the phototherapy threshold. Neonatal infection was defined as any antibiotic treatment before discharge.

Results

A total of 1360 newborn infants were included. Two hundred and three (14.9%) newborn infants developed hyperbilirubinemia in the first 48h of life. Hyperbil

SUBMITTER: Kardum D 

PROVIDER: S-EPMC9432075 | biostudies-literature | 2021 Jul-Aug

REPOSITORIES: biostudies-literature