Association between the FTO gene polymorphism and obesity in Brazilian adolescents from the Northeast region.

ABSTRACT:

Objective

To investigate the association between the FTO gene polymorphism with obesity in Brazilian adolescents from the Northeast region.

Method

This was a case-control study with adolescents aged 18 to 19 years. The case group consisted of 378 obese individuals and the control group of 378 non-obese individuals. Obesity was measured by percentage of body fat using the air displacement plethysmography technique. The study variables included data on socioeconomics, demographics, lifestyle, physical activity, waist circumference, waist-to-height ratio, and body mass index. To identify the rs9939609 polymorphism of the FTO gene, blood samples were obtained for genomic DNA extraction by the real-time PCR (Polymerase Chain Reaction) technique. Categorical variables were compare

SUBMITTER: Rodrigues LDS 

PROVIDER: S-EPMC9432123 | biostudies-literature | 2020 Sep - Oct

REPOSITORIES: biostudies-literature