Topographical Analysis of Aneurysm Wall Enhancement With 3-Dimensional Mapping.

ABSTRACT:

Background

Aneurysm wall enhancement has been identified as a potential biomarker for aneurysm instability. Enhancement has been determined by different approaches on 2D multiplanar views. This study describes a new method to quantify enhancement through 3D heatmaps and histograms.

Methods

A custom algorithm was developed using orthogonal probes extending from the aneurysm lumen into the wall to create 3D heatmaps and histograms of wall enhancement on 7T-MRI. Three quantitative metrics for general, specific, and focal wall enhancement were generated from the histograms.

Results

Thirty-two aneurysms were analyzed and classified based on 3D heatmaps and histograms. Larger aneurysms were more enhancing (Spearman's r=0.472, p=0.006), and had more heterogeneous enhancement

SUBMITTER: Raghuram A 

PROVIDER: S-EPMC9432773 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature