Prognostic value of serial score measurements of the national early warning score, the quick sequential organ failure assessment and the systemic inflammatory response syndrome to predict clinical outcome in early sepsis.

ABSTRACT:

Background and importance

Sepsis is a common and potentially lethal syndrome, and early recognition is critical to prevent deterioration. Yet, currently available scores to facilitate recognition of sepsis lack prognostic accuracy.

Objective

To identify the optimal time-point to determine NEWS, qSOFA and SIRS for the prediction of clinical deterioration in early sepsis and to determine whether the change in these scores over time improves their prognostic accuracy.

Design

Post hoc analysis of prospectively collected data.

Settings and participants

This study was performed in the emergency department (ED) of a tertiary-care teaching hospital. Adult medical patients with (potential) sepsis were included.

Outcome measures and analysis

The primary outcome wa

SUBMITTER: Zonneveld LEEC 

PROVIDER: S-EPMC9432814 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature