Continuous theta burst stimulation for drug-resistant epilepsy.

ABSTRACT:

Introduction

Repetitive transcranial magnetic stimulation (rTMS) may have anti-epileptic effects, especially in patients with neocortical lesions. Initial clinical trials demonstrated that the duration of the seizure reducing effect is relatively short-lived. In the context of a chronic condition like epilepsy, theta burst stimulation (TBS) may represent a potential solution in optimizing treatment practicality and durability as it was demonstrated to be associated with longer-lasting after-effects. TBS has been studied extensively in diverse neuropsychiatric conditions, but a therapeutic TBS protocol has not previously been applied in epilepsy patients.

Materials and methods

We performed a prospective open-label pilot study of 4-day accelerated continuous TBS (cTBS) treatme

SUBMITTER: Carrette S 

PROVIDER: S-EPMC9433314 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature