Fluid Accumulation After Neonatal Congenital Cardiac Operation: Clinical Implications and Outcomes.

ABSTRACT:

Background

This study was conducted to determine the association between fluid balance metrics and mortality and other postoperative outcomes after neonatal cardiac operation in a contemporary multicenter cohort.

Methods

This was an observational cohort study across 22 hospitals in neonates (≤30 days) undergoing cardiac operation. We explored overall percentage fluid overload, postoperative day 1 percentage fluid overload, peak percentage fluid overload, and time to first negative daily fluid balance. The primary outcome was in-hospital mortality. Secondary outcomes included postoperative duration of mechanical ventilation and intensive care unit (ICU) and hospital length of stay. Multivariable logistic or negative binomial regression was used to determine independent associ

SUBMITTER: Bailly DK 

PROVIDER: S-EPMC9433462 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature