Characterizing pharmacogenetic programs using the consolidated framework for implementation research: A structured scoping review.

ABSTRACT: Several healthcare organizations have developed pre-emptive pharmacogenetic testing programs, where testing is undertaken prior to the prescription of a medicine. This review characterizes the barriers and facilitators which influenced the development of these programs. A bidirectional citation searching strategy identified relevant publications before a standardized data extraction approach was applied. Publications were grouped by program and data synthesis was undertaken using the Consolidated Framework for Implementation Research (CFIR). 104 publications were identified from 40 programs and 4 multi-center initiatives. 26 (66%) of the programs were based in the United States and 95% in high-income countries. The programs were heterogeneous in their design and scale. The Characteristics

SUBMITTER: McDermott JH 

PROVIDER: S-EPMC9433561 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature