Evaluating the relationship between right-to-left shunt and white matter hyperintensities in migraine patients: A systematic review and meta-analysis.

ABSTRACT:

Introduction

White matter hyperintensities (WMHs) have been observed with greater frequency in patients with migraine and are thought to be associated with impaired cognition and function. The relationship between WMHs and right-to-left shunt (RLS) in migraine patients is unknown. We performed a systematic review to determine if there is an association between RLS and WMHs in patients with migraine.

Methods

A systematic search of the literature was performed in PubMed and Embase using a suitable keyword search strategy from inception up to 16th June 2021. All studies that included patients with migraine and studied RLS and WMHs were included.

Results

A total of 8 non-randomized observational studies comprising 1125 patients with migraine were included; 576 had an RLS,

SUBMITTER: Yeo JYP 

PROVIDER: S-EPMC9433673 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature