Comparison of non-criteria antiphospholipid syndrome with definite antiphospholipid syndrome: A systematic review.

ABSTRACT:

Objectives

Patients with laboratory or clinical manifestations suggestive of antiphospholipid syndrome (APS) but not fulfilling the classification criteria constitute a clinical challenge. This study aims to compare non-criteria APS (NC-APS) with definite APS in terms of clinical manifestations, therapies, and outcomes.

Methods

A systematic review of observational studies comparing definite and NC-APS was performed searching four electronic databases. Data on clinical manifestations, therapies and clinical outcomes was extracted.

Results

Sixteen studies, assessing a total of 3,798 participants, were included. Seven out of 10 studies found no significant difference in the prevalence of arterial or venous thrombosis between definite and NC-APS, with two studies on seron

SUBMITTER: Pires da Rosa G 

PROVIDER: S-EPMC9434011 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature