Predictive factors of clinical success after adrenalectomy in primary aldosteronism: A systematic review and meta-analysis.

ABSTRACT:

Background

Unilateral adrenalectomy is the mainstay treatment for unilateral primary aldosteronism (PA). This meta-analysis aimed to systematically analyse predictors of clinical success after unilateral adrenalectomy in PA.

Methods

A search was performed using PubMed/Medline, Scopus, Embase and Web of Science from their inception to February 2022. Observational studies in adult PA patients which reported predictors of clinical success after unilateral adrenalectomy were included. A random-effects model was employed to pool the fully adjusted odds ratio (OR) or standardized mean difference (SMD) with 95% confidence interval (95% CI).

Results

Thirty-two studies involving 5,601 patients were included. Females had a higher clinical success rat

SUBMITTER: Manosroi W 

PROVIDER: S-EPMC9434311 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature