Assisted Reproductive Technology and Risk of Childhood Cancers.

ABSTRACT:

Importance

The number of children born through the use of assisted reproductive technology (ART) has been increasing. These children may have higher risks for epigenetic alteration and adverse perinatal outcomes, which may be associated with childhood cancers.

Objective

To determine the associations between different modes of conception and childhood cancers and potential mediation by preterm birth and low birth weight.

Design, setting, and participants

This nationwide, population-based cohort study included registry data from 2 308 016 eligible parents-child triads in Taiwan from January 1, 2004, to December 31, 2017. A total of 1880 children with incident childhood cancer were identified. Data were analyzed between September 1, 2020, and June 30, 2022.

Exposure</

SUBMITTER: Weng SS 

PROVIDER: S-EPMC9434352 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature