Sex-specific performance of the ASCVD pooled cohort equation risk calculator as a correlate of coronary artery calcium in Kampala, Uganda.

ABSTRACT:

Introduction

The prevalence of cardiovascular disease (CVD) is rising in Sub-Saharan Africa, but it is not known whether current risk assessment tools predict coronary atherosclerosis in the region. Furthermore, sex-specific performance and interaction with HIV serostatus has not been well studied.

Methods

This cross-sectional study compared ASCVD risk scores and detectable coronary artery calcium (CAC>0) by sex in Kampala, Uganda (n = 200). The cohort was enriched for persons living with HIV, and all participants had at least one CVD risk factor. We fit log binomial regression models and constructed ROC curves to assess the correlation between ASCVD scores and CAC>0.

Results

The mean age was 56. 62% were female and 50% of both men and women were living with HIV. The

SUBMITTER: Kentoffio K 

PROVIDER: S-EPMC9434411 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature