Brain-Heart Link in Schizophrenia: Cognitive Inhibitory Control Deficit in Patients Is Specifically Related to Parasympathetic Dysregulation.

ABSTRACT:

Background

This study examined the connection between two prominent deficits in schizophrenia: the deficit in parasympathetic regulation and the deficit in cognitive inhibitory control, within the framework of the Neurovisceral Integration Model (NIM).

Study design

Thirty healthy controls and 30 patients with schizophrenia performed the internationally standardized antisaccade protocol while their electrocardiographic data were recorded. The interaction between the group, the cognitive inhibitory control as measured with error rate (ER) in the antisaccade task and parasympathetic activity as measured with the High Frequency power component of Heart Rate Variability (HF-HRV) was tested.

Study results

Findings confirmed that decreased HF-HRV was specifically related to

SUBMITTER: Lazaridi M 

PROVIDER: S-EPMC9434444 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature