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Anatomical Differences Between Human and Pig Hearts and Their Relevance for Cardiac Xenotransplantation Surgical Technique.


ABSTRACT: Cardiac xenotransplantation has been proposed to bridge the gap between supply and demand for patients with end-stage heart failure requiring transplantation. However, differences in pig anatomy compared with human anatomy require modification of the surgical approach. In addition, careful consideration should be given to size matching before transplantation. (Level of Difficulty: Advanced.).

SUBMITTER: Shah A 

PROVIDER: S-EPMC9434648 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature

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Anatomical Differences Between Human and Pig Hearts and Their Relevance for Cardiac Xenotransplantation Surgical Technique.

Shah Aakash A   Goerlich Corbin E CE   Pasrija Chetan C   Hirsch Jeffrey J   Fisher Stacy S   Odonkor Patrick P   Strauss Erik E   Ayares David D   Mohiuddin Muhammad M MM   Griffith Bartley P BP  

JACC. Case reports 20220707 16


Cardiac xenotransplantation has been proposed to bridge the gap between supply and demand for patients with end-stage heart failure requiring transplantation. However, differences in pig anatomy compared with human anatomy require modification of the surgical approach. In addition, careful consideration should be given to size matching before transplantation. (<b>Level of Difficulty: Advanced.</b>). ...[more]

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