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Visible-Light-Mediated Three-Component Cascade Sulfonylative Annulation.

ABSTRACT: Visible-light-promoted cascade radical cyclization for the synthesis of sulfonylated benzimidazo/indolo[2,1-a]iso-quinolin-6(5H)-ones has been reported. The reaction provides transition-metal-free and expeditious access to sulfonylated polyaromatics. The use of sodium metabisulfite as a SO₂ surrogate and the rapid generation of molecular complexity using a three-component photochemical protocol are the salient features of this reaction manifold.

SUBMITTER: Upreti GC

PROVIDER: S-EPMC9434776 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature

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Visible-Light-Mediated Three-Component Cascade Sulfonylative Annulation.

Upreti Ganesh Chandra GC Singh Tavinder T Ranjan Sudhir S Gupta Raju Kumar RK Singh Anand A

ACS omega 20220818 34

Visible-light-promoted cascade radical cyclization for the synthesis of sulfonylated benzimidazo/indolo[2,1-a]iso-quinolin-6(5H)-ones has been reported. The reaction provides transition-metal-free and expeditious access to sulfonylated polyaromatics. The use of sodium metabisulfite as a SO2 surrogate and the rapid generation of molecular complexity using a three-component photochemical protocol are the salient features of this reaction manifold. ...[more]

PMID: 36061680

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