Validation of age- and sex-dependent association of uric acid and incident hypertension in rural areas.

ABSTRACT:

Background

A previous study based on urban areas suggested the age- and sex-dependent association of uric acid (UA) and incident hypertension. We aimed to investigate whether this association is valid even in rural areas with different lifestyle.

Methods

Data from the cardiovascular disease association study, a prospective cohort study based on rural residents, was analyzed. A total of 4,592 subjects (mean age, 60.1 ± 9.5 years; men, 37.7%) without hypertension were included. We first investigated whether UA was a risk factor for incident hypertension using Cox regression, and then compared the relative risk by stratification according to age and sex.

Results

During the follow-up period (mean, 2.0 years), 579 subjects (12.6%) were newly diagnosed with hypertension. Th

SUBMITTER: Kim IJ 

PROVIDER: S-EPMC9434906 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature