The impact of brain invasion criteria on the incidence and distribution of WHO grade 1, 2, and 3 meningiomas.

ABSTRACT:

Background

In 2016 brain invasion was added as a standalone diagnostic criterion for Grade 2 meningiomas in the WHO Classification of Brain Tumors. The aim of this study was to compare the incidence and distribution of meningiomas, and agreement, between the 2007 and 2016 WHO criteria.

Methods

All cases of intracranial meningiomas diagnosed between 2007 and 2020 at a tertiary care academic hospital were identified. The incidence of each meningioma grade in the WHO 2007 and WHO 2016 cohorts were compared. Additionally, each case in the 2007 cohort was re-graded according to the WHO 2016 criteria to determine the intra-class correlation (ICC) between criteria.

Results

Of 814 cases, 532 (65.4%) were in the 2007 WHO cohort and 282 (34.6%) were in the 2016 WHO cohort. Ther

SUBMITTER: Rebchuk AD 

PROVIDER: S-EPMC9435498 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature