Vortex vein congestion in the monkey eye: A possible animal model of pachychoroid.

ABSTRACT:

Purpose

To create vortex vein congestion in the monkey eye as a possible pachychoroid model.

Methods

We ligated superotemporal and inferotemporal vortex veins at the surface of the sclera in monkey eyes. Optical coherence tomography (OCT) and indocyanine green angiography (ICGA) were performed before and 2, 7, and 28 days after the vortex vein ligations to investigate changes in vortex vein morphology and alterations in choroidal blood flow.

Results

Before the vortex vein ligations, en face OCT and ICGA images showed well organized vortex veins as well as horizontal and vertical watershed zones. Two days after the vortex vein ligations, dilatation of the superotemporal and inferotemporal vortex veins as well as intervortex venous anastomoses were seen on en face OCT a

SUBMITTER: Matsumoto H 

PROVIDER: S-EPMC9436071 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature