The epidemiology and evolution of IgA nephropathy over two decades: A single centre experience.

ABSTRACT:

Background and objectives

IgA nephropathy (IgAN) is the most common glomerulonephritis worldwide, with an incidence of 2.5 per 100,000 population per year. The 10-year risk of progression to end stage kidney disease (ESKD) or halving of eGFR is 26%. Here we aimed to collect a comprehensive dataset of IgAN patients at our centre over 2 decades to provide real world data, describe outcomes and determine the effects of immunosuppression use.

Design, setting, participants and measurements

All patients diagnosed with biopsy-proven IgAN at our centre over 2 decades were identified. After exclusions, the total cohort size was 401. Data relating to (i) baseline demographics, (ii) laboratory and urine results, (iii) histological data, and (iv) outcomes of initiation of renal replacem

SUBMITTER: Storrar J 

PROVIDER: S-EPMC9436111 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature