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Anti-inflammatory agents as modulators of the inflammation in adipose tissue: A systematic review.


ABSTRACT: Obesity is characterized by an adipose tissue mass expansion that presents a risk to health, associated with a chronic increase in circulating inflammatory mediators. Anti-inflammatory agents are an obesity alternative treatment. However, the lack of effective agents indicates the need to assess the mechanisms and identify effective therapeutic targets. The present work identified and described the mechanisms of action of anti-inflammatory agents in adipose tissue in experimental studies. The review was registered in the International Prospective Registry of Systematic Reviews (PROSPERO-CRD42020182897). The articles' selection was according to eligibility criteria (PICOS). The research was performed in PubMed, ScienceDirect, Scopus, Web of Science, VHL, and EMBASE. The methodological quali

SUBMITTER: da Cruz Nascimento SS 

PROVIDER: S-EPMC9436134 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature