Multimodal nocturnal seizure detection: Do we need to adapt algorithms for children?

ABSTRACT:

Objective

To assess the performance of a multimodal seizure detection device, first tested in adults (sensitivity 86%, PPV 49%), in a pediatric cohort living at home or residential care.

Methods

In this multicenter, prospective, video-controlled cohort-study, nocturnal seizures were detected by heartrate and movement changes in children with epilepsy and intellectual disability. Participants with a history of >1 monthly major motor seizure wore Nightwatch bracelet at night for 3 months. Major seizures were defined as tonic-clonic, generalized tonic >30 s, hyperkinetic, or clusters (>30 min) of short myoclonic or tonic seizures. The video of all events (alarms and nurse diaries) and about 10% of whole nights were reviewed to classify major seizures, and minor or no seizures.<

SUBMITTER: Lazeron RHC 

PROVIDER: S-EPMC9436288 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature