Psychophysiological interaction analysis for the detection of stimulus-specific networks in reflex epilepsy.

ABSTRACT: We report detailed functional MRI (fMRI) analyses in a patient with reflex seizures elicited by driving along a specific rural crossroad or by watching a video thereof. Semiology consisted of epigastric aura, followed by a sensory seizure of the left hand and sporadic automotor seizures. The right amygdala-region (rh-amygdala) was surgically and electroclinically confirmed as the epileptogenic zone. Presurgical task-fMRI was performed, during which videos of the driving along that specific crossroad (IC), of another crossroad (NC) or noise were presented. Independent component analysis was conducted, and one component was used to aid in selection of a seed region within the rh-amygdala for subsequent psychophysiological interaction analysis (PPI). Here, the following regions showed stronge

SUBMITTER: Zahnert F 

PROVIDER: S-EPMC9436291 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature