Pathological tumor long-to-short axis ratio as a prognostic factor in patients with thymic epithelial tumors.

ABSTRACT:

Background

Thymic epithelial tumors (TETs) exhibit irregular shapes reflective of the heterogeneity in tumor growth and invasive properties. We aimed to identify the prognostic value of the pathological tumor long-to-short axis (L/S) ratio in TETs.

Methods

A retrospective study was performed on patients with TETs who underwent extended thymectomy between January 1999 and December 2019 in our institute. Patients were divided into two groups according to the threshold of the L/S ratio. Overall survival (OS) and progression-free survival (PFS) were evaluated by Kaplan-Meier analysis. The independent prognostic factors of TETs were identified by multivariate analysis. The performance of prediction models for the above survival outcomes with and without the L/S ratio was evaluate

SUBMITTER: Tian D 

PROVIDER: S-EPMC9436687 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature