Hierarchically structural layered double oxides with stretchable nanopores for highly effective removal of protein-bound uremic toxins.

ABSTRACT: The global outbreak and prevalence of coronavirus disease 2019 (COVID-19) has triggered an urgent demand for family hemodialysis equipment. It is particularly vital to design and apply superior adsorbents to adsorb toxins for reducing the usage of dialysate. In this work, hierarchically structural MgAl layered double oxides (LDO) with stretchable nanopores were exploited through a facile one-pot trisodium citrate (TSC) assistant hydrothermal reaction followed by calcination treatment for effectively adsorbing protein-bound uremic toxins such as hippuric acid (HA) or indoxyl sulfate (IS). The optimized MgAl LDO possessed flower-like spherical morphology, ultrahigh specific surface area (187.3 m²/g) and uniquely stretchable nanopores, which were more conducive to incorporating ani

SUBMITTER: Ding S 

PROVIDER: S-EPMC9436783 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature