Effects of high-intensity interval training with hyperbaric oxygen.

ABSTRACT: Hyperbaric Oxygen (HBO₂) has been proposed as a pre-conditioning method to enhance exercise performance. Most prior studies testing this effect have been limited by inadequate methodologies. Its potential efficacy and mechanism of action remain unknown. We hypothesized that HBO₂ could enhance aerobic capacity by inducing mitochondrial biogenesis via redox signaling in skeletal muscle. HBO₂ was administered in combination with high-intensity interval training (HIIT), a potent redox stimulus known to induce mitochondrial biogenesis. Aerobic capacity was tested during acute hypobaric hypoxia seeking to shift the limiting site of whole body V̇O2 from convection to diffusion, more closely isolating any effect of improved oxidative capacity. Healthy volunteers we

SUBMITTER: Alvarez Villela M 

PROVIDER: S-EPMC9437248 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature