Urine metabolomics analysis of sleep quality in deep-underground miners: A pilot study.

ABSTRACT:

Background

In previous questionnaire surveys of miners, sleep disorders were found among underground workers. The influence of the special deep-underground environment and its potential mechanism are still unclear. Therefore, this study intends to utilize LC-MS metabolomics to study the potential differences between different environments and different sleep qualities.

Methods

Twenty-seven miners working at 645-1,500 m deep wells were investigated in this study, and 12 local ground volunteers were recruited as the control group. The Pittsburgh Sleep Quality Index (PSQI) was used to examine and evaluate the sleep status of the subjects in the past month, and valuable basic information about the participants was collected. PSQI scores were obtained according to specific calcul

SUBMITTER: Wen Q 

PROVIDER: S-EPMC9437423 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature