Development of Cumulative Order-Preserving Image Transformation Based Variational Autoencoder for Anterior Segment Optical Coherence Tomography Images.

ABSTRACT:

Purpose

To develop a variational autoencoder (VAE) suitable for analysis of the latent structure of anterior segment optical coherence tomography (AS-OCT) images and to investigate possibilities of latent structure analysis of the AS-OCT images.

Methods

We retrospectively collected clinical data and AS-OCT images from 2111 eyes of 1261 participants from the ongoing Asan Glaucoma Progression Study. A specifically modified VAE was used to extract six symmetrical and one asymmetrical latent variable. A total of 1692 eyes of 1007 patients were used for training the model. Conventional measurements and latent variables were compared between 74 primary angle closure (PAC) and 51 primary angle closure glaucoma (PACG) eyes from validation set (419 eyes of 254 patients) that were not

SUBMITTER: Shon K 

PROVIDER: S-EPMC9437650 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature