The incidence of fractures at various sites in newly treated patients with type 2 diabetes mellitus.

ABSTRACT:

Purpose

In this descriptive study, we examined the incidence of fractures in patients with newly treated type 2 diabetes mellitus (T2D) compared to matched reference population.

Methods

Participants from the UK Clinical Practice research datalink (CPRD) GOLD (1987-2017), aged ≥30 years, with a T2D diagnosis code and a first prescription for a non-insulin anti-diabetic drug (n = 124,328) were included. Cases with T2D were matched by year of birth, sex and practice to a reference population (n = 124,328), the mean follow-up was 7.7 years. Crude fracture incidence rates (IRs) and incidence rate ratios (IRRs) were calculated. Analyses were stratified by fracture site and sex and additionally adjusted for BMI, smoking status, alcohol use and history of any fracture at index date.

SUBMITTER: Sarodnik C 

PROVIDER: S-EPMC9437792 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature