Washed preparation of faecal microbiota changes the transplantation related safety, quantitative method and delivery.

ABSTRACT: The safety, quantitative method and delivery of faecal microbiota transplantation (FMT) vary a lot from different countries in practice. Recently, the improved methodology of FMT based on the automatic filtration, washing process and the related delivery was named as washed microbiota transplantation (WMT). First, this study aimed to describe the methodology development of FMT from manual to washing preparation from 2012 to 2021 in China Microbiota Transplantation System (CMTS), a centralized stool bank for providing a national non-profit service. The secondary aim is to describe donor screenings, the correlation between faecal weight and treatment doses, incidence of adverse events and delivery decision. The retrospective analysis on the prospectively recorded data was performed. Results

SUBMITTER: Lu G 

PROVIDER: S-EPMC9437882 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature