Development of high quality T₁-weighted and diffusion tensor templates of the older adult brain in a common space.

ABSTRACT: High-quality T₁-weighted (T₁w) and diffusion tensor imaging (DTI) brain templates that are representative of the individuals under study enhance the accuracy of template-based neuroimaging investigations, and when they are also located in a common space they facilitate optimal integration of information on brain morphometry and diffusion characteristics. However, such multimodal templates have not been constructed for the brain of older adults. The purpose of this work was threefold: (A) to introduce an iterative method for construction of multimodal T₁w and DTI templates that aims at maximizing the quality of each template separately as well as the spatial matching between templates, (B) to use this method to develop T₁w and DTI templates of the

SUBMITTER: Wu Y 

PROVIDER: S-EPMC9437946 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature