Protocol for an observational study investigating hormones triggering the onset of sustained lactation: the INSIGHT study.

ABSTRACT:

Introduction

Lactation is a hormonally controlled process that promotes infant growth and neurodevelopment and reduces the long-term maternal risk of diabetes, cardiovascular disease and breast cancer. Hormones, such as prolactin and progesterone, mediate mammary development during pregnancy and are critical for initiating copious milk secretion within 24-72 hours post partum. However, the hormone concentrations mediating lactation onset are ill defined.

Methods and analysis

The primary objective of the investigating hormones triggering the onset of sustained lactation study is to establish reference intervals for the circulating hormone concentrations initiating postpartum milk secretion. The study will also assess how maternal factors such as parity, pregnancy comorbiditie

SUBMITTER: Rostom H 

PROVIDER: S-EPMC9438014 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature