Continuous local anaesthetic wound infusion of bupivacaine for postoperative analgesia in neonates: a randomised control trial (CANWIN Study).

ABSTRACT:

Objective

To determine the effect of continuous wound infusion of local anaesthetic drug (bupivacaine) on total amount of systemic opioid use in the first 72 hours in newborn infants undergoing laparotomy.

Design

A two-arm parallel, open-label randomised controlled trial.

Setting

A quaternary newborn intensive care unit.

Patients

Infants>37 weeks of gestation undergoing laparotomy for congenital or acquired abdominal conditions.

Interventions

Continuous wound infusion of local anaesthetic (bupivacaine) for the first 72 hours along with systemic opioid analgesia (catheter group) or only systemic opioid analgesia (opioid group).

Main outcome

Total amount of systemic opioid used within the first 72 hours post laparotomy.

Results

The stu

SUBMITTER: Popat H 

PROVIDER: S-EPMC9438020 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature