Risk factors for neonatal sepsis in Sub-Saharan Africa: a systematic review with meta-analysis

ABSTRACT:

Objectives

To identify the risk factors for neonatal sepsis in Sub-Saharan Africa.

Design

Systematic review and meta-analysis.

Data sources

PubMed, Embase, Web of Science, African Index Medicus and ClinicalTrials.gov were searched for observational studies from January 2010 to August 2020.

Setting

Sub-Saharan Africa, at all levels of healthcare facilities.

Participants

‘Neonates’ (<28 days of age) at risk of developing either clinical and/or laboratory-dependent diagnosis of sepsis.

Outcome measures

Identification of any risk factors for neonatal sepsis.

Results

A total of 36 studies with 23 605 patients from secondary or tertiary level of care facilities in 10 countries were included. Six studies were rated as good quality, 8

SUBMITTER: Bech C 

PROVIDER: S-EPMC9438195 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature